Glut4 molecular weight
WebGLUT3 has at least a fivefold greater transport capacity than GLUT1 or GLUT4, as well as a higher glucose affinity than GLUT1, GLUT2 or GLUT4. ... Glucose delivery and utilization in the mammalian brain is mediated primarily by a high molecular weight form of GLUT1 in the blood–brain barrier, GLUT3 in neuronal populations and a less ... WebMonoclonal Antibody for studying Glut4. Cited in 185 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Glut4 (1F8) Mouse …
Glut4 molecular weight
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WebSkeletal muscle both stores glucose as glycogen and oxidizes it to produce energy following the transport step. The principal glucose transporter protein that mediates this uptake is … WebMar 1, 2001 · Labeled GLUT4 protein was quantified by integrating the area under the 3 H peak corresponding to the 45-kDa molecular weight marker and subtracting the …
WebApr 4, 2007 · GLUT4 is one of 13 sugar transporter proteins (GLUT1-GLUT12, and HMIT) encoded in the human genome (Joost and Thorens, 2001, Wood and Trayhurn, 2003) that catalyzes hexose transport across cell membranes through an ATP-independent, facilitative diffusion mechanism (Hruz and Mueckler, 2001).These sugar transporters display … WebThe glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the sarcolemma and t-tubule and, over the longer term, total GLUT4 protein content. Here, we review key aspects of GLUT4 biology in relation to exercise, with a focus on exercise …
WebGLUT4 (SLC2A4) is the insulin-responding glucose transporter, found predominantly in muscle cells and adipocytes (fat cells). After a meal, glucose that is absorbed from the digestive system and circulates in the blood now stimulates the release of insulin from the pancreas (Figure 4.10).This insulin is the signal for a rapid transfer of GLUT4 in muscle … WebAug 13, 2024 · Abundant expression of non-glycosylated GLUT1/Glut1 with an apparent molecular mass of 45 kDa was observed in astrocyte of human, monkey, ...
WebMolecular Biology • PCR & qPCR • RT-PCR ... GLUT4-IN-2 is a potent and selective GLUT4 inhibitor with IC 50 s of 11.4 µM and 6.8 µM for GLUT1 and GLUT4, …
Webpre-existing GLUT4 protein provides the major mechanism accounting for the acute insulin-stimulated glucose uptake that occurs in the post-prandial state (1, 3, 5, 6). In addition to this acute regulation of GLUT4-containing vesicle trafficking, the expression of GLUT4 is transcriptionally regulated in a variety of persistent altered metabolic ... cabbed zero turn mowerWebSep 2, 2012 · GLUT4 has long been known to be an insulin responsive glucose transporter. Regulation of GLUT4 has been a major focus of research on the cause and prevention of type 2 diabetes. Understanding … cabbed zero turn mowersWebGlut4/SLC2A4 Protein Molecular Weight & PI . Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4) Homo sapiens (Human). The parameters … clover trialWebOxidative matrine, also known as oxymatrine (OMT), with a molecular weight of 264.36 (molecular formula C 15 H 24 N 2 O 2 ), is an alkaloid with a variety of pharmacological activities, which is ... clover trial sepsisWeb1/100 - 1/1000. Predicted molecular weight: 54 kDa. IHC-P 1/100 - 1/500. Flow Cyt (Intra) 1/100. Target. Function. Insulin-regulated facilitative glucose transporter. Tissue specificity. ... Anti-Glucose Transporter GLUT4 … c.a.b. beefWebGlut4 (IF8): sc-53566 ... Molecular Weight of Glut4: 50-63 kDa. STORAGE Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. … cabbeen clothing china co. ltdWebAug 1, 2001 · Insulin resistance represents a major pathogenic impairment in the development of type 2 diabetes (1,2).In humans and rodents, skeletal muscle is the primary site of insulin-mediated glucose disposal ().Insulin increases glucose uptake in muscle by eliciting GLUT4 translocation from an intracellular storage site to both the plasma … cabbeen fashion ltd